Invitrogen™ CCDC36 Monoclonal Antibody (OTI2D11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526980

Catalog No. PIMA526980

Description

CCDC36 Monoclonal Antibody for Western Blot, IHC (P)

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

Specifications

• Antigen: CCDC36
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8IYA8
• Gene Symbols: CCDC36
• Immunogen: Full length human recombinant protein of CCDC36 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2D11
• Conjugate: Unconjugated
• Gene: CCDC36
• Gene Alias: Cancer/testis antigen 74; Ccdc36; coiled-coil domain containing 36; coiled-coil domain-containing protein 36; CT74; IHO1; Interactor of HORMAD1 protein 1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 339834
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid