CCDC36 Mouse anti-Human, Clone: OTI2D11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526980
DescriptionRequired for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|CCDC36; Coiled-coil domain-containing protein 36; Cancer/testis antigen 74|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of CCDC36 produced in E.coli|
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