Tocris™ CCG 1423

Induces intermediate mesoderm differentiation from ESCs; Rho/SRF pathway inhibitor

Manufacturer: Tocris™ 5233/50

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Catalog No. 52-335-0

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For Research Use Only


    Product Type CCG 1423
    Inhibitors CCG 1423
    Purity >99
    Molecular Weight 454.75
    Quantity 50mg

    Rho/SRF pathway inhibitor; stimulates apoptosis of a melanoma cell line overexpressing RhoC (A375M2). Suppresses Rho-dependent invasion of PC-3 prostate cancer cells in vitro and inhibits lysophosphatidic acid-induced DNA synthesis in PC-3 prostate cancer cells. When used in combination with Retinoic acid, LY 294002 and Pyridone 6, it induces intermediate mesoderm differentiation from ESCs.

    • Chemical Name: N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)benzamide
    • Formula: C18H13ClF6N2O3
    • CAS Number: 285986-88-1
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >99

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