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CCL16/HCC-4/LEC Mouse anti-Human, Clone: LEC67, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2328580.1MG

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Catalog No. NBP232858A


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Description

Description

CCL16/HCC-4/LEC Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Enzyme Linked Immunosorbent Assay, Functional Assay.
Specifications

Specifications

CCL16/HCC-4/LEC
LEC67
ELISA, Functional, SDS-Page
O15467
C-C motif chemokine 16, chemokine (C-C motif) ligand 16, Chemokine CC-4, Chemokine LEC, CKb12, HCC-4Liver-expressed chemokine, LCC-1Lymphocyte and monocyte chemoattractant, LEC, liver CC chemokine-1, LMCSmall-inducible cytokine A16, monotactin-1, MTN-1, NCC4IL-10-inducible chemokine, NCC-4ILINCK, new CC chemokine 4, SCYA16MGC117051, SCYL4, small inducible cytokine subfamily A (Cys-Cys), member 16
Mouse
IgG1 Kappa
Protein A purified
RUO
Primary
6360
Human
ELISA, Functional Assay, SDS-Page
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
Purified
CCL16
Recombinant human HCC-4 protein
11 kDa
0.1 mg
Store at 4C.
Monoclonal
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.
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