Invitrogen™ CCL3L1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596214

Catalog No. PIPA596214

Description

Immunogen sequence: APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA; Positive Samples: B-cell.

This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants.

Specifications

• Antigen: CCL3L1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCL3L1
• Gene Alias: 464.2; C-C motif chemokine 3-like 1; C-C motif chemokine ligand 3 like 1; CC-chemokine (CCL3); MIP1a; CCL3L1; CCL3L3; chemokine (C-C motif) ligand 3-like 1; chemokine ligand 3-like 1; D17S1718; G0/G1 switch regulatory protein 19-2; G0S19-2; LD78; LD78BETA; LD78-beta(1-70); LD78-beta(3-70); LD78-beta(5-70); macrophage inflamatory protein 1 alpha; MIP1AP; PAT 464.2; SCYA3L; SCYA3L1; small inducible cytokine A3-like 1; Small-inducible cytokine A3-like 1; Tonsillar lymphocyte LD78 beta protein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6349
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.51 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P16619
• Gene Symbols: CCL3L1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-93 of human CCL3L1 (NP_0662861).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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