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CCM2 Mouse anti-Human, Clone: OTI2E4, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503416S

Catalog No. 50-167-4318


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Description

Description

This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

CCM2
Monoclonal
Unconjugated
CCM2
Liquid
CCM2
Full length human recombit protein of human CCM2 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI2E4
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9BSQ5
C7orf22, OSM, PP10187
Mouse
IgG1
30 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
83605
Documents
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