CD100 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA551094
CD100 / SEMA4D Polyclonal Antibody detects endogenous levels of CD100 / SEMA4D protein.Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
|Synthesized peptide derived from the N-terminal region of human CD100.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|ELISA, Western Blot|
|PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4|
|Semaphorin-4D, CD100, BB18, A8, GR3, C9orf164, SEMAJ|
|-20° C, Avoid Freeze/Thaw Cycles|
|10507, 20354, 306790|
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