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CD105 (Endoglin) Rat anti-Mouse, Clone: MJ7/18, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$74.50 - $273.00

Specifications

Antigen CD105 (Endoglin)
Clone MJ7/18
Target Species Mouse
Conjugate Unconjugated
Isotype IgG2a, kappa
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-127-97 Non-distribution product as customer accommodation.
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Invitrogen
14105181
50 μg
Each for $74.50
Add to cart
 
50-127-98 Non-distribution product as customer accommodation.
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Invitrogen
14105182
100 μg
Each for $107.00
Add to cart
 
50-127-99 Non-distribution product as customer accommodation.
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Invitrogen
14105185
500 μg
Each for $273.00
Add to cart
 
Description

Description

Description: The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin. This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis. Applications Reported: The MJ7/18 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), and immunohistochemical staining of frozen tissue sections. Applications Tested: The MJ7/18 antibody has been tested by flow cytometric analysis of bEnd.3 cells or mouse splenocytes. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Specifications

Specifications

CD105 (Endoglin)
Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C
MJ7/18
Unconjugated
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.

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