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CD117/c-kit, Mouse anti-Human, Alexa Fluor 488, Clone: C117/370 + KIT/982 + KIT/983, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP247845AF488

Catalog No. NB007413


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Description

Description

CD117/c-kit Monoclonal antibody specifically detects CD117/c-kit in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence.
Specifications

Specifications

CD117/c-kit
C117/370 + KIT/982 + KIT/983
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Conjugated, Purified
KIT
Recombinant human CD117 proteins
Protein A or G purified
RUO
Store at 4°C in the dark.
Monoclonal
Human
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin)
Alexa Fluor 488
50mM Sodium Borate with 0.05% Sodium Azide
CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Mouse
IgG1 Kappa/IgG1 Kappa/IgG1 Kappa
0.1 mL
B Cell Development and Differentiation Markers, Cancer, Cancer Stem Cells, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid derived Suppressor Cell, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers, Tyrosine Kinases
Primary
This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
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