CD117/c-Kit/SCF-Receptor Ab-3 Mouse Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments.

Supplier:  Epredia MS289P1

Catalog No. MS289P1

Description

c-kit is a transmembrane receptor tyrosine kinase. It binds to stem cell factor (SCF). It is expressed in many tissues and cells. C-kit/SCf is involved in development of several lineages of stem cells, such as germ cells, neural crest-derived melanocytes and hematopoietic precursor cells. Ab-3 does not interfere with the binding of SCF to c-kit

Host Species: Mouse

Clone: K45

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Extracellular second N-terminus Ig-like domain of c-kit

Immunogen: Recombinant human extracellular c-kit fragment

Molecular Weight: 145kDa

Positive Control: Skin, GI Stromal Tumor (GIST)

Cellular Localization: Membrane/cytoplasmic

Recommended for:

• Immunohistochemistry (Frozen or fixed in methacarn or Stieve's and embedded in paraffin)
• Immunofluorescence

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: CD117/c-Kit/SCF-Receptor Ab-3
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 500 μL
• Primary or Secondary: Primary
• Form: Concentrated

• Applications: Immunofluorescence, Immunohistochemistry (Frozen)
• Clone: K45
• Conjugate: Unconjugated
• Immunogen: Recombinant human extracellular c-kit fragment
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG2a