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CD117/c-Kit/SCF-Receptor Ab-3 Mouse Monoclonal Antibody, Epredia™
Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments.
Supplier: Epredia MS289P1ABX
Description
c-kit is a transmembrane receptor tyrosine kinase. It binds to stem cell factor (SCF). It is expressed in many tissues and cells. C-kit/SCf is involved in development of several lineages of stem cells, such as germ cells, neural crest-derived melanocytes and hematopoietic precursor cells. Ab-3 does not interfere with the binding of SCF to c-kitHost Species: Mouse
Clone: K45
Isotype: IgG2a
Species Reactivity: Human. Others not known.
Epitope: Extracellular second N-terminus Ig-like domain of c-kit
Immunogen: Recombinant human extracellular c-kit fragment
Molecular Weight: 145kDa
Positive Control: Skin, GI Stromal Tumor (GIST)
Cellular Localization: Membrane/cytoplasmic
Recommended for:
- Immunohistochemistry (Frozen or fixed in methacarn or Stieve's and embedded in paraffin)
- Immunofluorescence
Note:
USA: RUO; Int'l: RUO
Specifications
CD117/c-Kit/SCF-Receptor Ab-3 | |
Monoclonal | |
1mg/mL | |
Mouse | |
100 μL | |
Primary | |
Concentrated |
Immunofluorescence, Immunohistochemistry (Frozen) | |
K45 | |
Unconjugated | |
Recombinant human extracellular c-kit fragment | |
RUO | |
Human | |
IgG2a |
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