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CD117/c-Kit/SCF-Receptor Rabbit Polyclonal Antibody, Epredia™
Optimize staining of formalin-fixed, paraffin-embedded tissues with Epredia™ CD117/c-Kit/SCF-Receptor, Rabbit Polyclonal Antibody.
Supplier: Epredia RB9038RQ
Description
Recognizes a protein of 145kDa, which is identified as CD117/p145kit. This rabbit polyclonal antibody does not interfere with the binding of SCF to c-kit. It precipitates both the unoccupied as well as the occupied form of c-kit. The binding of the stem cell factor (SCF) to the c-kit-encoded receptor tyrosine kinase (Type III) stimulates a variety of biochemical responses that culminate in cellular proliferation, migration, or survival. C-kit plays an important role in hematopoiesis, melanogenesis, and gametogenesis. This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human and Dog. Others not tested
Epitope: Cytoplasmic domain
Immunogen: A synthetic peptide from the cytoplasmic domain of human CD117/c-kit protein
Molecular Weight: 145 kDa
Positive Control: Stromal tumor, skin or tonsil
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Specifications
| CD117/c-Kit/SCF-Receptor | |
| Polyclonal | |
| Unconjugated | |
| A synthetic peptide from the cytoplasmic domain of human CD117 / c-kit protein | |
| IVD | |
| Ready-to-Use |
| Immunohistochemistry (Paraffin) | |
| Polyclonal | |
| Rabbit | |
| 12 mL | |
| Primary |
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