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CD119 (IFN gamma Receptor 1) Armenian Hamster anti-Mouse, PE, Clone: 2E2, eBioscience™ Non-distribution product as customer accommodation.

Armenian Hamster Monoclonal Antibody

$83.75 - $193.00

Specifications

Antigen CD119 (IFN gamma Receptor 1)
Clone 2E2
Target Species Mouse
Conjugate PE
Isotype IgG
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-105-80 Non-distribution product as customer accommodation.
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Invitrogen
12119180
25 μg Each for $83.75
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50-112-2260 Non-distribution product as customer accommodation.
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Invitrogen
12119182
100 μg Each for $193.00
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Description

Description

Description: The monoclonal antibody 2E2 recognizes mouse CD119 also known as IFN gamma receptor1. CD119 heterodimerizes with IFN gamma receptor 2 (AF-1) forming the Class II cytokine receptor. The ligand IFN gamma binds IFN gamma receptor 1 subunit but signal transduction transpires via the IFN gamma receptor 2 subunit. The receptor is involved in host defense and expression is broad including B cells, NK cells, macrophages and dendritic cells as well as other non-hematopoietic cell types. Applications Reported: This 2E2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 2E2 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. In addition, longer incubations appear to help stain the popµLation; therefore we recommend a 60 minute incubation at 2-8°C. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 µm post-manufacturing filtered.

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Specifications

Specifications

CD119 (IFN gamma Receptor 1)
Mouse
IgG
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
2E2
PE
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.

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