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CD11b, APC, clone: VIM12, Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen CD11B05

Catalog No. 50-112-1599


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Description

Description

CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X, and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, and blood monocytes. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue.

Allophycocyanin (APC) is a stable and highly soluble phycobiliprotein that provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing exceptional quantum yields and molar extinction coefficients.
Specifications

Specifications

CD11b
Monoclonal
APC
ITGAM
Liquid
ITGAM
Human CD11b (Mac-1)
Purified
ASR, ASR/IVD
Antibody
Monoclonal
Human
Flow Cytometry
VIM12
PBS with BSA and 0.1% sodium azide
P11215
CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6, Integrin alpha M
Mouse
IgG1
0.5mL
Store at 2 - 8 °C.
Primary
3684
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