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CD122 Mouse anti-Human, PE, Clone: TU27, eBioscience™ Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

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Catalog No. 12-122-842


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Description

Description

This TU27 monoclonal antibody reacts with human CD122, which is also known as interleukin-2 receptor beta (IL-2R beta). This receptor is expressed on NK cells, activated T cells, some B cells, monocytes, and T cell leukemias. CD122 can also be detected during early NK cell commitment. IL-2R beta associates with the IL-2R alpha (CD25) or IL-15R alpha and common gamma chain (CD132) to form the high affinity IL-2 and IL-15 receptors, respectively. By itself, this membrane receptor can bind IL-2, but with intermediate affinity. The binding of IL-2 results in internalization of the cytokine, tyrosine phosphorylation of IL-2Rbeta, and activation of signaling cascades such as the JAK/STAT pathway. Applications Reported: This TU27 antibody has been reported for use in flow cytometric analysis. Applications Tested: This TU27 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount ( μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser

CD122 Monoclonal antibody specifically detects CD122 in Human samples. It is validated for Flow Cytometry
Specifications

Specifications

CD122
Flow Cytometry
TU27
PE
Il2rb
CD122; CD122 antigen; high affinity IL-2 receptor beta subunit; High affinity IL-2 receptor subunit beta; IL-15 receptor beta chain; IL15RB; IL15Rbeta; IL-15Rbeta; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; Il-2/15Rbeta; IL-2R subunit beta; Il2rb; IL-2RB; IL2RBC; Il-2Rbeta; interleukin 15 receptor, beta; interleukin 2 receptor subunit beta; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; Interleukin-15 receptor subunit beta; Interleukin-2 receptor subunit beta; p70; P70-75; p75
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3560
Liquid
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P14784
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
SDS
Documents
Product Certifications
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