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CD13 Mouse anti-Human, FITC, Clone: WM-15 (WM15), eBioscience™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen 11013842

Catalog No. 50-112-9012


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Description

Description

Description: The WM-15 monoclonal antibody reacts with human CD13, also known as aminopeptidase N. CD13 is a transmembrane ectoenzyme occurring on monocytes and granulocytes but not lymphocytes in blood. It is also reportedly on a wide variety of cells and in a wide variety of tissues, including endothelial cells, epithelial cells, fibroblasts, kidney proximal tubules, intestine, and placenta. CD13 is reported to have many different functions including degradation of enkephalins and endorphins, terminal degradation of peptides, amino acid scavenging, antigen processing, and adhesion and migration of cells. Applications Reported: The WM-15 (WM15) antibody) has been reported for use in flow cytometric analysis. Applications Tested: This WM-15 (WM15) antibody has been pre-titrated and tested by flow cytometric analysis of lysed whole blood. This can be used at 5 µL (1 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.

CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.
Specifications

Specifications

CD13
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P15144
AP-M, AP-N, Apn, Cd13, P150, alanyl aminopeptidase, aminopeptidase M, aminopeptidase N, aminopeptidase N/CD13, membrane protein p161, microsomal aminopeptidase
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
WM-15 (WM15)
FITC
ANPEP
Liquid
ANPEP
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
290
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