CD131 Mouse anti-Human, Biotin, Clone: 1C1, eBioscience™ Invitrogen™
Mouse Monoclonal Antibody
The 1C1 monoclonal antibody reacts with the human CD131 molecule, also known as the common beta subunit (betaC). The common beta subunit associates with the specific alpha subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. Applications Reported: This 1C1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 1C1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount ( μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.CD131 Monoclonal antibody specifically detects CD131 in Human samples. It is validated for Flow Cytometry
|Ai2ca; AI848964; AIC2A; AIC2B; Bc; beta c; beta common cytokine receptor; BetaIl3; Bil3; CD antigen CD131; CD131; CD131 antigen; CDw131; colony stimulating factor 2 receptor beta common subunit; colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); colony-stimulating factor 2 receptor subunit beta-2; colony-stimulating factor-2 receptor, beta, low-affinity; common beta chain; CSF2RB; Csf2rb1; Csf2rb2; Csfgmrb; Cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 RB; IL-3 Receptor beta; IL-3 receptor class 2 subunit beta; Il3r; IL3R beta; IL-3R class 2 subunit beta; IL3RB; Il3rb1; Il3rb2; IL5RB; interleukin 3 common beta chain; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); interleukin-3 receptor class 2 subunit beta; Interleukin-3 receptor class II beta chain; SMDP5|
|4° C, store in dark, DO NOT FREEZE!|
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
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