Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ Lab Vision™ CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunofluorescence and flow cytometry applications with Thermo Scientific™ CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ MS621B

 View more versions of this product

Catalog No. MS621B


Add to cart

Description

Description

Ensure accurate, reproducible results in immunofluorescence and flow cytometry applications with Thermo Scientific™ CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody.

4-1BB (also known as CD137) is an inducible receptor-like protein expressed on the cell surface of activated splenic T cells and thymocytes. It exists as both a monomer and a dimer on the surface of activated T cells. 4-1BB is structurally related to the members of NGFR/TNFR superfamily which are characterized by the presence of three-six patterns of a cysteine-rich motif in their extracellular domains. Other members of this family include low affinity NGFR, two receptors for TNF (TNFR-I & TNFR-II), CD30, CD40, OX40, Fas, and CD27. These molecules are involved in cell growth, survival, and death processes. The cytoplasmic domain of 4-1BB include two runs of acidic amino acids, a potential p56lck binding site, five consecutive glycines at the C-terminus, and four potential phosphorylation sites: one tyrosine, two threonine, and one serine.

Host Species: Mouse

Clone: BBK-2

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Ectodomain

Immunogen: Ectodomain of human 4-1BB recombinant protein

Molecular Weight: 30kDa

Positive Control: Spleen, thymus or tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

CD137 Ab-1
Monoclonal
200μg/mL
Concentrated
Ectodomain of human 4-1BB recombinant protein
1mL
Apoptosis
Primary
Human
Flow Cytometry, Immunofluorescence
BBK-2
Biotin
Murine
IgG1 kappa
RUO
Primary
Monoclonal
SDS
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit