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CD137 (4-1BB) Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ CD137 (4-1BB) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

$728.00 - $1222.00

Specifications

Antigen CD137 Ab-1
Clone BBK-2
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Form Concentrated
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Products 7
Catalog Number Mfr. No. Conjugate Concentration Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Conjugate Concentration Quantity Price Quantity & Availability  
MS621B1
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Epredia
MS621B1
Biotin 200μg/mL 500 μL
Each for $746.00
Add to Cart
 
MS621P1
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Epredia
MS621P1
Unconjugated 200μg/mL 500 μL
Each for $728.00
Add to Cart
 
MS621P1ABX
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Epredia
MS621P1ABX
Unconjugated 1mg/mL 100 μL
Each for $847.00
Add to Cart
 
MS621PABX
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Epredia
MS621PABX
Unconjugated 1mg/mL 200 μL
Each for $1,222.00
Add to Cart
 
MS621B0
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Epredia
MS621B0
Biotin 200μg/mL 100 μL Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area. N/A
MS621B
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Epredia
MS621B
Biotin 200μg/mL 1 mL Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area. N/A
MS621P0
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Epredia
MS621P0
Unconjugated 200μg/mL 100 μL Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area. N/A
Description

Description

4-1BB (also known as CD137) is an inducible receptor-like protein expressed on the cell surface of activated splenic T cells and thymocytes. It exists as both a monomer and a dimer on the surface of activated T cells. 4-1BB is structurally related to the members of NGFR/TNFR superfamily which are characterized by the presence of three-six patterns of a cysteine-rich motif in their extracellular domains. Other members of this family include low affinity NGFR, two receptors for TNF (TNFR-I & TNFR-II), CD30, CD40, OX40, Fas, and CD27. These molecules are involved in cell growth, survival, and death processes. The cytoplasmic domain of 4-1BB include two runs of acidic amino acids, a potential p56lck binding site, five consecutive glycines at the C-terminus, and four potential phosphorylation sites: one tyrosine, two threonine, and one serine.

Host Species: Mouse

Clone: BBK-2

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Ectodomain

Immunogen: Ectodomain of human 4-1BB recombinant protein

Molecular Weight: 30kDa

Positive Control: Spleen, thymus or tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

CD137 Ab-1
Flow Cytometry, Immunofluorescence
Concentrated
RUO
Human
IgG1 κ
BBK-2
Monoclonal
Mouse
Apoptosis
Ectodomain of human 4-1BB recombinant protein
Primary
SDS
Documents

Documents

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