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CD137 Ligand Mouse, anti-Human, R718, Clone: C65-485, BD OptiBuild™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 752131

Catalog No. BDB752131


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Description

Description

The C65-485 monoclonal antibody specifically recognizes the type II membrane protein known as 4-1BB Ligand (4-1BB-L) or CD137 Ligand (CD137L). This molecule belongs to the TNF superfamily and is encoded by TNFSF9 (Tumor necrosis factor superfamily member 9). CD137 Ligand has been reported to have costimulatory function on activated T cells. Reports suggest that stimulation of activated T cells via CD137 Ligand does not require the presence of other costimulatory molecules, including CD28. Some studies have reported human CD137 Ligand to be expressed preferentially on primary B cells and B-cell lines. The C65-485 antibody is able to react with recombinant human 4-1BB Ligand (rh4-1BB-L/CD137L) bound to CD137 (4-1BB receptor) expressed on phytohemagglutinin (PHA)-stimulated PBMC.

Specifications

Specifications

CD137 Ligand
C65-485
Liquid
50 μg
Refrigerate Upon Arrival
Monoclonal
Flow Cytometry
R718
Mouse
RUO
Primary
Human
SDS
Documents
Product Certifications
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