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CD14 Mouse anti-Human, Brilliant Violet 786, Clone: M5E2, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 563698
Description
The M5E2 monoclonal antibody specifically binds to CD14, a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.
The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon™ BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).
Specifications
CD14 | |
Monoclonal | |
Brilliant Violet 786 | |
Mouse | |
Affinity Purified | |
RUO | |
Baboon, Canine, Cynomolgus, Human, Rhesus Monkey | |
IgG2a κ |
Flow Cytometry | |
M5E2 | |
LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein | |
Human CD14 Protein | |
100 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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For Research Use Only.