Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
CD14 Mouse anti-Human, Clone: OTI3D6, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA811529
SDSDocumentsProduct Certifications Promotions
DescriptionCD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|Human recombit protein fragment corresponding to amino acids 20-367 of human CD14 produced in E.coli.|
Provide Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok