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CD140a (PDGFRA) Rat anti-Mouse, APC-eFluor 780, Clone: APA5, eBioscience
Rat Monoclonal Antibody
Manufacturer: eBioscience 47140180
Description
The APA5 monoclonal antibody reacts with the mouse CD140a molecule, the alpha chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRa is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylate
00-8222-49) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No. 00-5333-57) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 633-647 nm; Emission: 780 nm; Laser: Red Laser PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.Specifications
CD140a (PDGFRA) | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
P26618 | |
Pdgfra | |
IgG2a, kappa | |
25 μg | |
4° C, store in dark, DO NOT FREEZE! | |
Primary | |
18595 |
Flow Cytometry | |
APA5 | |
APC-eFluor™ 780 | |
Pdgfra | |
Liquid | |
Rat | |
Affinity Chromatography | |
RUO | |
Antibody | |
Monoclonal | |
Mouse |
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