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CD140a (PDGFRA) Rat anti-Mouse, APC-eFluor™ 780, Clone: APA5, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Manufacturer:  eBioscience 47140182

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Catalog No. 47-140-182


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Description

Description

The APA5 monoclonal antibody reacts with the mouse CD140a molecule, the alpha chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRa is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylate

00-8222-49) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No. 00-5333-57) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 633-647 nm; Emission: 780 nm; Laser: Red Laser PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Specifications

Specifications

CD140a (PDGFRA)
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P26618
Pdgfra
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
18595
Flow Cytometry
APA5
APC-eFluor™ 780
Pdgfra
Liquid
Rat
Affinity Chromatography
RUO
Antibody
Monoclonal
Mouse
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