Thermo Scientific™ Lab Vision™ CD141/Thrombomodulin Ab-1, Mouse Monoclonal Antibody

Optimize immunohistochemical staining of formalin-fixed tissue using Thermo Scientific™ CD141/Thrombomodulin Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ MS1102R7

Catalog No. MS1102R7

Description

Optimize immunohistochemical staining of formalin-fixed tissue using Thermo Scientific™ CD141/Thrombomodulin Ab-1, Mouse Monoclonal Antibody.

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

Host Species: Mouse

Clone: 141C01; same as 1009

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: EGF domain

Immunogen: Recombinant protein encoding the six repeated EGF domains of human thrombomodulin

Molecular Weight: 75kDa

Positive Control: Mesothelioma

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: CD141
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Murine
• Isotype: IgG2a kappa
• Regulatory Status: RUO
• Type: Primary
• Monoclonal or Polyclonal: Monoclonal

• Applications: Immunohistochemistry (Paraffin)
• Clone: 141C01; same as 1009
• Format: Prediluted
• Immunogen: Recombinant protein encoding the six repeated EGF domains of human thrombomodulin
• Quantity: 7mL
• Research Discipline: Hematopoietic
• Primary or Secondary: Primary
• Target Species: Human, Rat