CD147 Mouse anti-Human, PE, Clone: 8D12, eBioscience™ Invitrogen™
Mouse Monoclonal Antibody
The monoclonal antibody 8D12 recognizes CD147 which is a member of the immunoglobulin superfamily. It is also called EMMPRIN and basigin. CD147 has been characterized as a tumor cell collagenase stimulating molecule and has also been shown to have a role in cell adhesion. CD147 can be found in association with integrins alpha3 beta1 and alpha6 beta1 by co-immpunopreciptations. Additionally it is thought to play a role in T cell activation and thymocyte cycling. CD147 is expressed broadly on hematopoietic and non-hematopoietic cells, especially in tumor cells. Applications Reported: This 8D12 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 8D12 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.CD147 Monoclonal antibody specifically detects CD147 in Human samples. It is validated for Flow Cytometry
|5A11; 5A11/Basigin; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); Bsg; CD147; CE9; collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; Glycoprotein CE9; gp 42; HT7; HT-7; HT7 antigen; Leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; TCSF; Tumor cell-derived collagenase stimulatory factor; UNQ6505/PRO21383|
|4° C, store in dark, DO NOT FREEZE!|
|PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2|
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