CD15 Ab-3 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry and flow cytometry procedures with Epredia™ CD15 Ab-3, Mouse Monoclonal Antibody.

Supplier:  Epredia MS1259P0

Catalog No. MS1259P0

Description

3-fucosyl-N-acetyllactosamine (3-FAL) or CD15 or X-hapten plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Host Species: Mouse

Clone: MMA; same as LeuM1

Isotype: IgM/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: U937 histiocytic cell line

Molecular Weight: 220kDa

Positive Control: Reed-Sternberg's cells in Hodgkin's lymphoma

Cellular Localization: Membrane and granular paranuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Flow Cytometry

Specifications

• Antigen: CD15 Ab-3
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Oncogenesis
• Target Species: Human
• Isotype: IgM κ

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Clone: MMA; same as LeuM1
• Conjugate: Unconjugated
• Immunogen: U937 histiocytic cell line
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Concentrated