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CD16/CD32 Rat anti-Mouse, PE, Clone: FCR-4G8, Invitrogen™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MFCR04

Catalog No. 50-113-8122


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Description

Description

CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.
Specifications

Specifications

CD16/CD32
Monoclonal
0.1 mg/mL
PBS with 0.1% sodium azide
P08101
FCGR3, FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, FCGR2, CD32, Fc gamma Receptor II, CD32 receptor 2, Fc gamma Receptor 2, FCGR2A, FCGR2B, FCGR2C, Low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, FCG2, Low affinity immunoglobulin gamma Fc region receptor II-c, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, FGFR2B
Rat
IgG2b
1 mL
4° C
Primary
14130
Flow Cytometry
FCR-4G8
PE
Fcgr2b
Liquid
Fcgr2b
Mouse CD16/32 (Blocks Fc gamma,RIII/II).
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Documents
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