CD160 Mouse anti-Human, PE, Clone: BY55, eBioscience
Mouse Monoclonal Antibody
Manufacturer: Invitrogen 12160942
Description: This BY55 monoclonal antibody reacts with human CD160, a member of the immunoglobulin superfamily expressed on natural killer cells, natural killer T cells, activated and/or memory CD4 and CD8 T cells, gamma delta T cells, and intraepithelial cells. CD160 has been reported to bind herpes virus entry mediator (HVEM) in a complex with LIGHT and BTLA to deliver an inhibitory signal to CD4 T cells that abrogates proliferation and cytokine production. Three alternative splice variants of CD160 have also been identified in natural killer cells. Applications Reported: This BY55 antibody has been reported for use in flow cytometric analysis. Applications Tested: This BY55 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 µm post-manufacturing filtered.CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. It is involved in cell proliferation, cell surface receptor signaling pathways, cellular defense response, and regulation of immune response.
|PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2|
|NK1, NK28, CD160 antigen, CD160 transmembrane isoform, CD160-delta Ig, natural killer cell receptor BY55, natural killer cell receptor|
|4° C, store in dark, DO NOT FREEZE!|
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