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CD182 Mouse anti-Human, Brilliant Violet 605, Clone: 6C6, BD Optibuild™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 744197

Catalog No. BDB744197


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Description

Description

The 6C6 monoclonal antibody specifically binds to CD182. CD182 is also known as the interleukin-8 receptor B (IL-8RB), a G-protein-linked seven transmembrane domain protein, expressed on monocytes and granulocytes. It is also expressed on a subset of T cells. Both IL-8RA (CXCR1) and IL-8RB (CXCR2) are high affinity receptors for IL-8. IL-8 is an inflammatory cytokine which induces chemotaxis of neutrophils, basophils and T lymphocytes.

This antibody is conjugated to BD Horizon™ BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407nm and Em Max of 602nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20nm filter set. BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605nm. Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers. BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser. BV605 is a tandem fluorochrome that combines BD Horizon BV421 and Cy™3.5. These conjugates are very bright, exhibiting similar brightness to equivalent PE conjugates. Due to the excitation of Cy3.5 by the green (532nm) and yellow-green (561nm) lasers, there will be significant spillover of the BD Horizon BV605 signal into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD182
6C6
Brilliant Violet 605
CXCR2, CXCR-2, IL8RB, IL-8Rβ, Interleukin 8 receptor, beta, CDw128b
Human CXCR2 Transfected Cell Line
50 μg
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
0.2mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Mouse
Affinity Purified
RUO
Human
IgG1 λ
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