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CD19 Mouse anti-Human, Monkey, Primate, APC, Clone: CVID3/429, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP261909APC

Catalog No. NBP261909AP


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Description

Description

CD19 Monoclonal antibody specifically detects CD19 in Human, Monkey, Primate samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD19
CVID3/429
Flow Cytometry
Conjugated, Purified
CD19
Recombinant human CD19 protein
Protein A or G purified
Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Primary
930
Human, Monkey, Primate
Flow Cytometry
APC
PBS with 0.05% Sodium Azide
B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Mouse
IgG1 Kappa
0.1 ml
Store at 4°C in the dark.
Monoclonal
CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms
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