CD1c Monoclonal Antibody (L161), NovaFluor™ Blue 610-70S, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
H046T02B06	LIFE TECHNOLOGIES H046T02B06	25 Tests
H046T03B06	LIFE TECHNOLOGIES H046T03B06	100 Tests

Description

This L161 monoclonal antibody detects CD1c (also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. Finally, alternative splicing gives rise to three different isoforms of CD1c (soluble, membrane, and cytoplasmic/soluble isoforms). Applications Reported: This L161 antibody has been reported for use in flow cytometric analysis. Applications Tested: This L161 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.06 μg) per test NovaFluor dyes are not compatible with DNA intercalating viability dyes. Do not use viability dyes such as propidium iodide, 7-actinomycin D (7-AAD) and DAPI. Invitrogen LIVE/DEAD Fixable Dead Cell stains are recommended for use with NovaFluor dyes. Each NovaFluor conjugate or kit is shipped with CellBlox Blocking Buffer. NovaFluor conjugates are based on Phiton technology utilizing novel nucleic acid dye structures that allow for engineered fluorescent signatures with consideration for spillover and spread impacts. Excitation: 509 nm; Emission: 614 nm; Laser: 488 nm (Blue) Laser

CD1c Monoclonal antibody specifically detects CD1c in Human samples. It is validated for Flow Cytometry

Specifications

• Antigen: CD1c
• Concentration: 0.2 μg/Test
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Alias: BDCA1; canCD1c; CD1; CD1A; CD1C; CD1C antigen, c polypeptide; CD1c molecule; cortical thymocyte antigen CD1C; differentiation antigen CD1-alpha-3; R7; RP11-101J8.3; T-cell surface glycoprotein CD1c
• Isotype: IgG1 κ
• Purification Method: Affinity chromatography
• Product Type: Antibody

• Clone: L161
• Applications: Flow Cytometry
• Conjugate: NovaFluor Blue 610-70S
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P29017
• Gene ID (Entrez): 911
• Primary or Secondary: Primary
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Gene: CD1C