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CD1c Monoclonal Antibody (L161), NovaFluor™ Blue 660-120S, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Specifications

Antigen CD1c
Clone L161
Concentration 0.2 μg/Test
Applications Flow Cytometry
Classification Monoclonal
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
H046T02B08
Encompass
View Documents
LIFE TECHNOLOGIES
H046T02B08
25 Tests This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
H046T03B08
Encompass
View Documents
LIFE TECHNOLOGIES
H046T03B08
100 Tests This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

This L161 monoclonal antibody detects CD1c (also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. Finally, alternative splicing gives rise to three different isoforms of CD1c (soluble, membrane, and cytoplasmic/soluble isoforms). Applications Reported: This L161 antibody has been reported for use in flow cytometric analysis. Applications Tested: This L161 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.06 μg) per test NovaFluor dyes are not compatible with DNA intercalating viability dyes. Do not use viability dyes such as propidium iodide, 7-actinomycin D (7-AAD) and DAPI. Invitrogen LIVE/DEAD Fixable Dead Cell stains are recommended for use with NovaFluor dyes. Each NovaFluor conjugate or kit is shipped with CellBlox Blocking Buffer. NovaFluor conjugates are based on Phiton technology utilizing novel nucleic acid dye structures that allow for engineered fluorescent signatures with consideration for spillover and spread impacts. Excitation: 509 nm; Emission: 665 nm; Laser: 488 nm (Blue) Laser

CD1c Monoclonal antibody specifically detects CD1c in Human samples. It is validated for Flow Cytometry
Specifications

Specifications

CD1c
0.2 μg/Test
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
BDCA1; canCD1c; CD1; CD1A; CD1C; CD1C antigen, c polypeptide; CD1c molecule; cortical thymocyte antigen CD1C; differentiation antigen CD1-alpha-3; R7; RP11-101J8.3; T-cell surface glycoprotein CD1c
IgG1 κ
Affinity chromatography
Antibody
L161
Flow Cytometry
NovaFluor Blue 660-120S
Mouse
Human
P29017
911
Primary
4° C, store in dark, DO NOT FREEZE!
CD1C
SDS
Product Certifications
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