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CD1d Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 173361AP

Catalog No. 50-173-1516


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Description

Description

CD1d is a 49 kDa heavy chain associated with Beta 2 microglobulin on cortical thymocytes. Beta 2 microglobulin independent expression of CD1d has also been demonstrated on human intestinal epithelial cells. CD1d is the sole group 2 member of the CD1 family of major histocompatibility (MHC) like glycoproteins. The CD1d gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by the CD1d gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease.
Specifications

Specifications

CD1d
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P11609, P15813
CD1A, CD1D, CD1d molecule, R3, R3G1
Rabbit
IgG
150 μL
-20°C
Primary
12479, 912
Western Blot
Unconjugated
CD1D
Liquid
CD1D, Cd1d1
CD1d Fusion Protein Ag11371
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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