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CD20 Antibody (rIGEL/773), Allophycocyanin/Cy7, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP254591APCCY7
Description
CD20 Monoclonal specifically detects CD20 in Human samples. It is validated for Flow Cytometry.Specifications
CD20 | |
Monoclonal | |
APC-Cyanine7 | |
PBS with 0.05% Sodium Azide | |
MS4A1 | |
Recombinant full-length human CD20 fragment (Uniprot: P11836) | |
0.1 mL | |
Primary | |
Recognizes a protein of 30-33kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre-B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This monoclonal antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly | |
Store at 4°C in the dark. Do not freeze. |
Flow Cytometry | |
rIGEL/773 | |
Flow Cytometry | |
B1, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35MGC3969, CD20 antigen, CD20 receptor, CD20S7, CVID5, LEU-16, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, MS4A2 | |
Mouse | |
Protein A or G purified | |
Adaptive Immunity, B Cell Development and Differentiation Markers, Cancer, Cancer Stem Cells, Cell Biology, Cytokine Research, Immunology, Signal Transduction, Stem Cell Markers, Tumor Biomarkers | |
931.0 | |
Human | |
IgG1 κ |
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