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CD20 Mouse anti-Human, DyLight 594, Clone: IGEL/773, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 1 publication

Manufacturer:  Novus Biologicals NBP247840DL594

Catalog No. NB247840594


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Description

Description

CD20 Monoclonal specifically detects CD20 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Multiplex Immunoassay.
Specifications

Specifications

CD20
IGEL/773
DyLight 594
50mM Sodium Borate with 0.05% Sodium Azide
B1, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35MGC3969, CD20 antigen, CD20 receptor, CD20S7, CVID5, LEU-16, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, MS4A2
Mouse
IgG2a Kappa
Protein A purified
Adaptive Immunity, B Cell Development and Differentiation Markers, Cancer Stem Cells, Cell Biology, Cytokine Research, Immunology, Signal Transduction, Stem Cell Markers, Tumor Biomarkers
Primary
931
Human
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
1 mg/mL
Western Blot 1 - 2 μg/mL, Flow Cytometry 0.5 - 1ug/million cells, ELISA 1-100-1:2000, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1 - 2 μg/mL, Immunohistochemistry-Paraffin 1 - 2 μg/mL, Immunohistochemistry-Frozen 1:10-1:500
Purified
MS4A1
Recombinant human CD3e fragment (aa 23-119)
20 kDa
0.1 ml
Store at 4C in the dark.
Monoclonal
Recognizes a protein of 30-33kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.
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