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CD205 Mouse anti-Human, Clone: HD30, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA528126

Catalog No. PIMA528126


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Description

Description

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
Specifications

Specifications

CD205
Monoclonal
1 mg/mL
PBS with no preservative
O60449
LY75
Purified extracellular domain of human CD205-IgG1 Fc fusion protein
Protein G
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
HD30
Unconjugated
LY75
Liquid
Mouse
IgG1
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
4065
Documents
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