CD205 Mouse anti-Human, Clone: HD30, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA528126
DescriptionCD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
|PBS with no preservative|
|Purified extracellular domain of human CD205-IgG1 Fc fusion protein|
|Flow Cytometry, Immunohistochemistry (Frozen), Western Blot|
|-20° C, Avoid Freeze/Thaw Cycles|
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