Epredia™ Lab Vision™ CD22 Ab-4, Mouse Monoclonal Antibody

Obtain accurate and reproducible results in immunohistochemistry experiments with Epredia™ CD22 Ab-4, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1087R1

Catalog No. MS1087R1

Description

CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types.In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells. CD22 is found highly expressed in follicular mantle and marginal zone B-cells, while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Host Species: Mouse

Clone: FPC1

Isotype: IgG1

Species Reactivity: Human. Others not tested.

Epitope: Extracellular

Immunogen: Recombinant protein encoding the external domain of human CD22

Molecular Weight: 130-140kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin only)

Specifications

• Antigen: CD22 Ab-4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant Protein encoding the external domain of human CD22
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Prediluted

• Applications: Immunohistochemistry (Paraffin)
• Clone: FPC1
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: B-Cell
• Target Species: Human
• Isotype: IgG1