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CD223 (LAG-3) Monoclonal Antibody (3DS223H), Brilliant Violet™ 711, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody


Antigen CD223 (LAG-3)
Clone 3DS223H
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
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25 Tests This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
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100 Tests This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A


This 3DS223H mAb recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells). This 3DS223H antibody will recognize a formaldehyde-fixed epitope. Applications Tested: This 3DS223H antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. BV 711 is a tandem dye that emits at 713nm and is intended for use on cytometers equipped with a violet (405nm) laser. When using two or more Super Bright, BV, BUV, or other polymer dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (SB-4401-42) or Brilliant Stain Buffer (00-4409-75) to minimize any non-specific polymer interactions. Excitation: 407nm; Emission: 713nm; Laser: Violet Laser. BV is a trademark or registered trademark of Becton, Dickinson and Company or its affiliates, and is used under license. Powered by Sirigen.

CD223 (LAG-3) Monoclonal antibody specifically detects CD223 (LAG-3) in Human samples. It is validated for Flow Cytometry


CD223 (LAG-3)
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
IgG1 κ
Affinity chromatography
Flow Cytometry
Brilliant Violet 711
4° C, store in dark, DO NOT FREEZE!
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