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CD249 (BP-1) Rat anti-Mouse, FITC, Clone: 6C3, eBioscience™

Rat Monoclonal Antibody

$101.00 - $181.00

Specifications

Antigen CD249 (BP-1)
Clone 6C3
Target Species Mouse
Conjugate FITC
Isotype IgG2a κ
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-989-7
Encompass
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Invitrogen
11589182
100 μg
Each for $181.00
Add to cart
 
11-589-181
Encompass
View Documents
Invitrogen
11589181
50 μg
Each for $101.00
Add to cart
 
Description

Description

Description: The 6C3 monoclonal antibody reacts with mouse BP-1, also known as Ly-51 and 6C3 antigen. BP-1 is a 140 kDa type II transmembrane protein that is present on the surface as a disulfide-linked homodimer. This molecule is an enzyme with aminopeptidase A (APA) activity and is expressed by bone marrow stromal cells, thymic cortical epithelial cells and at early stages of mouse B cell development, on pre-B cells. The low level of BP-1 expression on pre-B cells can be upregulated in the presence of IL-7. Applications Reported: The 6C3 antibody has been reported for use in flow cytometric analysis. Applications Tested: The 6C3 antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
Specifications

Specifications

CD249 (BP-1)
Mouse
IgG2a κ
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO
6C3
FITC
Flow Cytometry
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
SDS
Product Certifications

For Research Use Only.

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