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CD25/IL-2R alpha Human anti-Human, Cynomolgus Monkey, Rhesus Macaque, DyLight 488, Clone: Basiliximab, Novus Biologicals™

Human Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275902G

Catalog No. NBP275902G


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Description

Description

CD25/IL-2R alpha Monoclonal antibody specifically detects CD25/IL-2R alpha in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence.
Specifications

Specifications

CD25/IL-2R alpha
Basiliximab
Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence
Conjugated, Purified
IL2RA
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Protein A purified
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction
Primary
3559.0
Cynomolgus Monkey, Human, Rhesus Macaque
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
DyLight 488
50mM Sodium Borate with 0.05% Sodium Azide
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Human
IgG1 Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
SDS
Documents
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