CD25/IL-2R alpha Human anti-Human, Cynomolgus Monkey, Rhesus Macaque, DyLight 488, Clone: Basiliximab, Novus Biologicals
Human Monoclonal Antibody
Manufacturer: Novus Biologicals NBP275902G
DescriptionCD25/IL-2R alpha Monoclonal antibody specifically detects CD25/IL-2R alpha in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence.
|Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence|
|Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.|
|Protein A purified|
|Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction|
|Cynomolgus Monkey, Human, Rhesus Macaque|
|Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot|
|50mM Sodium Borate with 0.05% Sodium Azide|
|CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR|
|Store at 4°C in the dark.|
|Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.|
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