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CD25/IL-2R alpha Antibody (Basiliximab), Janelia Fluor™ 549 - Chimeric, Novus Biologicals™
Rabbit Monoclonal Antibody
Supplier: Novus Biologicals NBP252661JF549
Description
CD25/IL-2R alpha Monoclonal specifically detects CD25/IL-2R alpha in Human, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence.Specifications
CD25/IL-2R alpha | |
Monoclonal | |
Janelia Fluor 549 | |
50mM Sodium Borate with 0.05% Sodium Azide | |
IL2RA | |
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells. | |
0.1 mL | |
Primary | |
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation. | |
Store at 4°C in the dark. | |
IgG κ |
Flow Cytometry, Immunofluorescence, Immunohistochemistry | |
Basiliximab | |
Flow Cytometry, Immunohistochemistry, Immunofluorescence | |
CD25, CD25 antigen, IDDM10, IL-2 receptor subunit alpha, IL2R, IL-2R subunit alpha, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR | |
Rabbit | |
Protein A or G purified | |
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Biologically Active Proteins, Cytokine Research, Diabetes Research, Immunology, Innate Immunity, Mast Cell Markers, Signal Transduction | |
3559 | |
Human, Mouse, Rat, Cynomolgus Monkey, Rhesus Macaque | |
Purified |
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