CD274 (PD-L1, B7-H1) Rat anti-Mouse, Clone: 1-111A, eBioscience™ Invitrogen™
Rat Monoclonal Antibody
The 1-111A monoclonal antibody reacts with mouse B7-H1, also known as PD-L1. B7-H1, a member of the B7 family, has a predicted molecular weight of approximately 40 kDa and belongs to the Ig superfamily. B7-H1 is expressed on a majority of leukocytes including T, B, NK and DC. B7-H1 is a ligand for PD-1. Interaction of PD-1 with either PD-L1 (B7-H1) or PD-L2 (B7-DC) results in inhibition of T and B cell responses. Preliminary testing suggests that 1-111A and MIH5 (Cat. No. 14-5982) cross-block each other. Applications Reported: The 1-111A antibody has been reported for use in flow cytometric analysis. Applications Tested: The 1-111A antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.CD274 (PD-L1, B7-H1) Monoclonal antibody specifically detects CD274 (PD-L1, B7-H1) in Mouse samples. It is validated for Flow Cytometry
|CD274 (PD-L1, B7-H1)|
|A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; CD274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1|
|PBS with 0.09% sodium azide; pH 7.2|
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