CD28 Mouse anti-Human, Alexa Fluor™ 350, Clone: C28/77, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234576AF350
DescriptionCD28 Monoclonal specifically detects CD28 in Human samples. It is validated for ELISA.
|Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen|
|CD28 antigen, CD28 antigen (Tp44), CD28 molecule, MGC138290, T-cell-specific surface glycoprotein CD28, Tp44|
|Store at 4°C in the dark.|
|Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.|
|Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|Alexa Fluor 350|
|50 mM sodium borate with 0.05% sodium azide|
|Recombinant human CD28 protein|
|Protein A or G purified|
|Adaptive Immunity, Apoptosis, Cancer, Cell Biology, Immune System Diseases, Immunology, Neuroscience, Signal Transduction|
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