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CD28 Mouse anti-Human, Mouse, Porcine, Primate, Sheep, Janelia Fluor 646, Clone: 204.12, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP254769JF646

Catalog No. N254769J646


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Description

Description

CD28 Monoclonal antibody specifically detects CD28 in Human, Mouse, Porcine, Primate, Sheep samples. It is validated for Flow Cytometry, Immunocytochemistry, Immunofluorescence.
Specifications

Specifications

CD28
204.12
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Conjugated, Purified
CD28
Stimulated human leucocytes
Protein A or G purified
Adaptive Immunity, Apoptosis, Immunology
Primary
940.0
Human, Mouse, Porcine, Primate, Sheep
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Janelia Fluor 646
50mM Sodium Borate with 0.05% Sodium Azide
CD28 antigen, CD28 antigen (Tp44), CD28 molecule, MGC138290, T-cell-specific surface glycoprotein CD28, Tp44
Mouse
IgG2a Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
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