CD281 (TLR1) Rat anti-Mouse, Clone: eBioTR23 (TR23), eBioscience™ Invitrogen™
Rat Monoclonal Antibody
The eBioTR23 monoclonal antibody reacts with mouse Toll-like receptor 1 (TLR1, CD281). TLR1 is an approximately 98 kDa protein belonging to the Toll-like receptor family, and is closely-related to mouse TLR6 in both structure and function. Through the formation of a complex with TLR2, TLR1 is able to bind bacterially-derived triacyl lipopeptides, as well as soluble factors released from Neisseria meningitidis. TLR1 is expressed by macrophages and macrophages in TLR1-deficient mice display impaired production of inflammatory cytokines upon stimulation with triacyl lipopeptides and lipoproteins from mycobacteria. Applications Reported: This eBioTR23 (TR23) antibody has been reported for use in flow cytometric analysis, and immunoprecipitation. Applications Tested: This eBioTR23 (TR23) antibody has been tested by flow cytometric analysis of mouse TLR1-transfected Baf/3 cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.CD281 (TLR1) Monoclonal antibody specifically detects CD281 (TLR1) in Mouse samples. It is validated for Flow Cytometry, Immunoprecipitation
|Flow Cytometry, Immunoprecipitation|
|CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; Tlr1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1|
|PBS with 0.09% sodium azide; pH 7.2|
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok