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CD281 (TLR1) Rat anti-Mouse, Clone: eBioTR23 (TR23), eBioscience™ Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  LIFE TECHNOLOGIES 14901137


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Catalog No. 14-901-137

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The eBioTR23 monoclonal antibody reacts with mouse Toll-like receptor 1 (TLR1, CD281). TLR1 is an approximately 98 kDa protein belonging to the Toll-like receptor family, and is closely-related to mouse TLR6 in both structure and function. Through the formation of a complex with TLR2, TLR1 is able to bind bacterially-derived triacyl lipopeptides, as well as soluble factors released from Neisseria meningitidis. TLR1 is expressed by macrophages and macrophages in TLR1-deficient mice display impaired production of inflammatory cytokines upon stimulation with triacyl lipopeptides and lipoproteins from mycobacteria. Applications Reported: This eBioTR23 (TR23) antibody has been reported for use in flow cytometric analysis, and immunoprecipitation. Applications Tested: This eBioTR23 (TR23) antibody has been tested by flow cytometric analysis of mouse TLR1-transfected Baf/3 cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

CD281 (TLR1) Monoclonal antibody specifically detects CD281 (TLR1) in Mouse samples. It is validated for Flow Cytometry, Immunoprecipitation


CD281 (TLR1)
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
2 mg
IgG2a κ
Flow Cytometry, Immunoprecipitation
eBioTR23 (TR23)
CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; Tlr1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1
Affinity chromatography
4° C


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