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CD290 (TLR10) Mouse anti-Human, PE, Clone: 3C10C5, eBioscience™ Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Catalog No. 12-290-942


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Description

Description

This 3C10C5 monoclonal antibody reacts with human CD290, which is also known as Toll-like receptor 10 (TLR10). This type I transmembrane glycoprotein is expressed on B cells, monocytes, regulatory T cells (Tregs), and plasmacytoid dendritic cells. Moreover, CD290 expression is dependent on Foxp3 and NFAT in Tregs. Studies demonstrate that CD290 can self-dimerize, as well as heterodimerize with other members of the TLR family such as TLR1 and TLR2. Ligand binding results in association of the receptor with the adapter molecule MyD88 and subsequent activation of signaling pathways. Although the ligands of CD290 remain undefined, this receptor has been associated with the immune response against microbial and fungal infection and autoimmune diseases such as Crohn's disease and systemic lupus erythematosous. Applications Reported: This 3C10C5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 3C10C5 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD290 (TLR10) Monoclonal antibody specifically detects CD290 (TLR10) in Human samples. It is validated for Flow Cytometry
Specifications

Specifications

Liquid
Flow Cytometry
3C10C5
PE
TLR10
CD290; MGC104967; MGC126398; MGC126399; TLR10; toll like receptor 10; Toll-like receptor 10; UNQ315/PRO358
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
81793
CD290 (TLR10)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q9BXR5
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
SDS
Documents
Product Certifications
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