CD3d Mouse anti-Human, PE-Texas Red®, Clone: 7D6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MHCD0317
The R-phycoerythrin (PE)-Texas Red conjugate permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser.CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The CD3d protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in the CD3d gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms of CD3d have been found. Other variants of CD3d may also exist, but the full-length nature of their transcripts have yet to be defined.
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|Human CD3 delta|
|PBS with BSA, sucrose and 0.1% sodium azide|
|CD3-DELTA, T3D, CD3 antigen, delta subunit, CD3 delta, CD3d antigen, delta polypeptide TiT3 complex, OKT3, delta chain, T-cell receptor T3 delta chain, T-cell surface glycoprotein CD3 delta chain, CD3/TCR complex|
|4° C, store in dark|
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