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CD3 Mouse, anti-Human, R718, Clone: UCHT1, BD Horizon™
Mouse Monoclonal Antibody
Supplier: BD Biosciences 566953
Description
The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.
Specifications
CD3 | |
Monoclonal | |
R718 | |
100 Tests | |
Primary | |
Refrigerate Upon Arrival |
Flow Cytometry | |
UCHT1 | |
Mouse | |
RUO | |
Human | |
Liquid |
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