CD300a Mouse anti-Human, PE, Clone: MEM-260, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen A15778
DescriptionCD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.
|HPB human lymphoid leukemia cell line.|
|PBS with 0.2% BSA and 15mM sodium azide|
|CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60, CD300 antigen-like family member A, CD300a antigen, CMRF35-like molecule 8, IGSF12|
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